In April 1994, China and Croatia signed the Agreement on Scientific and Technological Cooperation between the Government of the People’s Republic of China and the Government of the Republic of Croatia .

In October 1997, China and Croatia signed the Agreement on the Establishment of the China-Croatia Intergovernmental Committee for Scientific and Technological Cooperation between the Government of the People’s Republic of China and the Government of the Republic of Croatia. Since 1998, scientific and technological exchanges between the two sides have gradually deepened and yielded fruitful results with a total of 165 exchange projects being supported. The China-Croatia Belt and Road Joint Laboratory on Biodiversity and Ecosystem Services has become a flagship and model of bilateral science, technology and innovation cooperation.

In May 2014, Vice Premier Liu Yandong visited Croatia and attended the unveiling ceremony of China-Croatia Ecological Conservation International Joint Research Center.

In April 2019, China and Croatia signed the Memorandum of Understanding on Jointly Funding Research and Development Cooperation Projects between the Ministry of Science and Technology of the People’s Republic of China and the Ministry of Science and Education of the Republic of Croatia, adding a new mechanism to take bilateral innovation cooperation to a new level.

In May 2023, the 10th Session of the China-Croatia Inter-governmental Committee for Scientific and Technological Cooperation was convened in China.